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The renin-aldosterone website link is mediated by angiotensin II, so coadministration of an angiotensin II receptor antagonist has a tendency to reverse the potassium reduction connected with these diuretics.
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Sufferers dealing with an overdose may possibly present with hypokalemia, hypochloremia, and hyponatremia. Take care of sufferers with symptomatic and supportive therapy which include fluids and electrolytes. Vasopressors could be administered to take care of hypotension and oxygen could possibly be given for respiratory impairment.
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The selection of Irbesartan & Hydrochlorothiazide tablets as Original therapy for hypertension ought to be determined by an evaluation of potential Added benefits and challenges.
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